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Clinical study of Angong Niuhuang Pill on acute ischemic brain injury

Efficacy and safety of Angong Niuhuang Pill in the treatment of severe ischemic stroke

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2100005279
Enrollment
Unknown
Registered
2021-09-05
Start date
2021-10-01
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic stroke

Interventions

experience group:Routine ischemic stroke treatment, and give Angong Niuhuang Pill 3G / time, nasal feeding or oral, once a day for 7 days

Sponsors

The first people's Hospital of Yuhang District, Hangzhou City, Zhejiang Province
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: (1) Over 18 years old; (2) Acute severe ischemic stroke (NIHSS score > 15); (3) Within 24 hours of onset; (4) The diagnosis of cerebral infarction was in line with the standards of Chinese guidelines for the diagnosis and treatment of acute ischemic stroke 2018; (5) The patient or the patient's agent signs the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Patients with acute cerebral infarction receiving thrombolysis or surgery; (2) Patients with end-stage status at admission (GCS score < 5 or mydriasis fixed); (3) History of intracranial hemorrhage, intracranial space occupying, brain trauma or other brain diseases; (4) Patients with severe liver insufficiency (CTP grade B or above) and severe renal insufficiency (CCR < 30ml / min); (5) Patients with primary diseases and malignant tumors of hematopoietic system and immune system; (6) Patients who refused or withdrew from the study due to various reasons.

Design outcomes

Primary

MeasureTime frame
28 day mortality;

Secondary

MeasureTime frame
Blood arsenic concentration;Urinary mercury concentration;Urinary arsenic concentration;Blood mercury concentration;Improvement rate of early consciousness;

Countries

China

Contacts

Public ContactYunlong Wu

The first people's Hospital of Yuhang District, Hangzhou City, Zhejiang Province

440103344@qq.com15372002502

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026