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A randomized controlled trial on the effectiveness and safety of acupuncture in the treatment of gastrointestinal dysfunction after chemotherapy for colorectal cancer

A randomized controlled trial on the effectiveness and safety of acupuncture in the treatment of gastrointestinal dysfunction after chemotherapy for colorectal cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2100005275
Enrollment
Unknown
Registered
2021-09-04
Start date
2021-08-30
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer

Interventions

waiting list group:NA
sham acupuncture group:sham acupuncture

Sponsors

Chengdu University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria require that the patients (1) males or females are between 18 and 75 years of age; (2) colonoscopy and histopathological biopsy diagnosed as primary colon cancer or primary high rectal cancer, staging I-III; (3) symptoms related to gastrointestinal dysfunction occurred after chemotherapy, including nausea, vomiting, abdominal distension, diarrhea, constipation, etc.; any item in the gastrointestinal symptom grading scale was scored above 2 points; (4) no abdominal surgery history or more than 3 months after abdominal surgery; (5) The Karnofsky score = 60 points, or the ECOG physical fitness score = 1 point, and the expected survival time is = 3 months; (6) have not received acupuncture treatment and have not participated in other clinical studies within the past 3 months; (7) at least one cycle of chemotherapy has been completed; (8) gastrointestinal dysfunction caused by non-opioids or metabolic imbalances.

Exclusion criteria

Exclusion criteria: Participants who meet one of the following criteria will be excluded: (1) have undergone total colorectal resection or who have a fistula; (2) with severe heart disease, cerebrovascular disease; (3) use warfarin, heparin, etc., or who have abnormal hematopoietic function; (4) unconsciousness, unable to express subjective symptoms and mental illness; (5) long-term use of laxatives, or taking drugs that affect gastrointestinal function and those who are bedridden for a long time.

Design outcomes

Primary

MeasureTime frame
Gastrointestinal symptom rating scale;

Secondary

MeasureTime frame
SAS;SDS;FACT-C(V 4.0);

Countries

Sichuan

Contacts

Public ContactFanrong Liang
acuresearch@126.com13608058216

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026