chronic atrophic gastritis
Conditions
Interventions
Treatment group:Weierkang Pills (Zhejiang Jiahe Pharmaceutical Co., Ltd., 0.32g/tablet) for treatment. Method of administration: 3 tablets/dose orally before meals, 3 times/day, for 6 months.
Sponsors
Xijing Hospital of Air Force Military Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Age 18-75 years, regardless of gender. (2) Patients with moderate to severe atrophy and/or intestinalization diagnosed by upper gastrointestinal endoscopy and gastric mucosal pathological tissue biopsy (at least 1 in the gastric sinus and at least 1 in the gastric body) within the last three months, i.e., patients with OLGA/OLGIM stage II-IV (moderate or greater atrophy/atrophy in at least one part of the gastric sinus and body), including those with low-grade intraepithelial neoplasia and those with high-grade intraepithelial neoplasia who do not wish to undergo surgical treatment. (3) Individuals who have been confirmed free of H. pylori infection or successfully eradicated by 13C-UBT. (4) Voluntary treatment with Weierkang pills.
Exclusion criteria
Exclusion criteria: (1) History of previous gastric surgery (including post-ESD, EMR) or with malignancy. (2) Patients with contraindications to the study drug or allergies to the study drug. (3) Pregnant and lactating women. (4) A history of drug abuse or alcohol abuse within the last 1 year. (5) Those with psychiatric disorders. (6) Those who are unable to cooperate in completing the treatment protocol (7) Refusal to sign an informed consent form. (8) Patients who are participating in other clinical trials. (9) Patients who, in the opinion of the investigator, are otherwise unsuitable for clinical observational studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Histopathological biopsy of gastric mucosa;gastroscopy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Gastrointestinal symptom Rating Scale; | — |
Countries
China
Contacts
Public ContactYonquan Shi
Xijing Hospital of Air Force Military Medical University
Outcome results
None listed