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Untargeted metabolomics and its association with intestinal microbiota metagenomics in diabetes mellitus with acute myocardial infarction (DM-AMI) patients with different

Untargeted metabolomics and its association with intestinal microbiota metagenomics in diabetes mellitus with acute myocardial infarction (DM-AMI) patients with different

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ITMCTR
Registry ID
ITMCTR2100005250
Enrollment
Unknown
Registered
2021-08-28
Start date
2021-09-01
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes mellitus,Acute myocardial infarction

Interventions

Severe blood stasis+AMI+T2DM:No intervention
Severe blood stasis+AMI without T2DM:No intervention
Mild blood stasis+AMI without T2DM:No intervention
Mild blood stasis+AMI+T2DM:No intervention

Sponsors

Xiyuan Hospital, China Academy of Chinese Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: ?The diagnosis of type 2 diabetes conforms to the diagnostic criteria of Guideline for the prevention and treatment of type 2 diabetes mellitus in China (2020 edition); ?Acute myocardial infarction diagnosis consistents with Guidelines for rapid Emergency Diagnosis and Treatment of Acute coronary syndrome (2019); ?Blood stasis syndrome of coronary heart disease score =19 points; ?Age =18 years old,irrespective of gender; ?Volunteer for this study, sign informed consent and with good patient compliance.

Exclusion criteria

Exclusion criteria: ?Acute complications of diabetes mellitus; ?Severe cerebrovascular disease, secondary hypertension, uncontrolled severe hypertension grade 3; ?Patients with hepatic and renal insufficiency of the progress period,malignant tumor, trauma and surgical history in recent months; ?Autoimmune diseases ,or associated with other diseases that affect glucose metabolism such as hyperthyroidism, acromegaly, and Cushing's syndrome; ?Other stress conditions combined with infection, inflammation, autoimmune diseases; ?Participated in other clinical investigators within the last 3 months; ?Pregnant and lactating women; ?Other conditions that the investigator considers inappropriate for participation in this clinical study; ?Severe mental illness.

Design outcomes

Primary

MeasureTime frame
Untargeted metabolomics;

Secondary

MeasureTime frame
Exosomes;Intestinal microbiota metagenomics;

Countries

China

Contacts

Public ContactYue Liu

Xiyuan Hospital, China Academy of Chinese Medical Sciences

liuyue@188.com13701167815

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026