Post-stroke aphasia
Conditions
Interventions
Control Group:Sham Acupuncture
Experimental group:Acupuncture
Sponsors
Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Diagnosed as stroke, 14 to 30 days after stroke onset; 2. Aged 18 years and above, and native language is Chinese, right-handed; 3. Primary school and above education; 4. Definite aphasia syndrome, diagnosed as Non-fluent aphasia after stroke by WAB; 5. The score of Boston Diagnostic Aphasia Examination (BDAE) is 2 to 4; 6. The language function and orientation were normal before the onset, with the distal muscle strength of unilateral upper limb grades greater than or equal to grade IV; 7. Be able to cooperate one-hour EEG/MRI examination; 8. Signed informed consent is obtained according to local ethical committee requirements.
Exclusion criteria
Exclusion criteria: 1. Severe hearing and visual impairment; 2. Superficial sensation abnormalities in the neurological examination; 3. Patients with dysarthria; 4. Language dysfunction caused by congenital or childhood diseases; 5. Patients who have received pacemaker surgery, coronary intervention, coronary artery bypass surgery and other metal products in the body, which cannot undergo MRI examination; 6. Patients who have serious heart, liver, and kidney diseases; 7. Patients with moderate or severe dementia, MMSE =< 20 points, education level above junior high school =< 24 points; 8. Patients who are unable to perform image naming task due to dysfunction such as agnosia, unilateral neglect, and hemiopia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in aphasia quotient from baseline to week 4; | — |
Secondary
| Measure | Time frame |
|---|---|
| Electroencephalo-graph;Severity of Aphasia;Quality of Life;Psychological assessment;Magnetic Resonance Imaging;Change in aphasia quotient from baseline to week 24;Safety index;Disease Prognosis Scale of ischaemic stroke;Degree of nervous functional defects;Cognitive Abilit;Activity of Daily Living; | — |
Countries
China
Contacts
Public ContactChang Jingling
Outcome results
None listed