knee osteoarthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) The diagnostic criteria of KOA conform to American College of Rheumatology (ACR); (2) Kellgren-Lawrence (K-L) staging is stage I, stage II or stage III; (3) The heart, lung, liver, and kidney functions are good, and they can tolerate ESWT; (4) No drugs or knee arthroscopic surgery has been used for treatment in the past 3 months; (5) The informed consent form was signed.
Exclusion criteria
Exclusion criteria: (1) Rheumatoid arthritis, rheumatoid arthritis, traumatic arthritis, gouty arthritis; (2) There is a wound on the affected knee or tuberculosis, infection, osteomyelitis in the affected limb; (3) Suffering from vascular and neurological diseases; (4) The affected knee has severe varus deformity; (5) Combining severe primary diseases such as liver, kidney, cardiovascular and cerebrovascular and hematopoietic systems diseases; (6) With severe osteoporosis; (7) Breast-feeding or pregnant women; (8) Those who cannot tolerate ESWT due to pain and other factors; (9) The content of knee joint fluid is too small to meet the testing needs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ROM;LKSS score;WOMAC scale;Lequesne index score;VAS score; | — |
Secondary
| Measure | Time frame |
|---|---|
| MMP-3;SOD;TNF-a;TGF-ß1;IL-1ß; | — |
Countries
China
Contacts
Shanghai Tenth People's Hospital