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A Randomized Controlled Study of Acupuncture Intervention for Subthreshold Depression

A Randomized Controlled Study of Acupuncture Intervention for Subthreshold Depression

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2100005147
Enrollment
Unknown
Registered
2021-08-07
Start date
2021-08-10
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Subthreshold Depression

Interventions

Sponsors

Affiliated Hospital of Shandong University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria for subthreshold depression; 2. Aged between 18-60 years, and the gender is not limited; 3. Hamilton-17-item Depression Scale (HAMD-17) score: 7 points <= HAMD <17 points; 4. Have not used any antidepressant drugs for at least 2 weeks before treatment, and have not received acupuncture treatment for depression in the past 3 months; 5. It is forbidden to take antibiotics, probiotics and fermented dairy products such as yogurt before entering the group and providing specimens; 6. Be able to actively cooperate with the treatment and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with clinically diagnosed depression, previous mental illness or organic mental disorder; 2. Those with severe liver and kidney damage, severe arrhythmia or cardiac insufficiency; 3. Pregnant and lactating patients; 4. Depressive episodes caused by psychoactive substances or non-addictive substances; 5. The patient has a strong suicide attempt or behavior; 6. Those who cannot tolerate acupuncture treatment; 7. Those who have communication difficulties or do not cooperate with the researcher; 8. Other situations judged by the investigator to be inappropriate for inclusion in the observation.

Design outcomes

Primary

MeasureTime frame
Hamilton depression scale;

Secondary

MeasureTime frame
Generalized anxiety scale;The proportion of people who developed moderate depression;9 items of patient health questionnaire;Quality of life scale SF12 2nd edition;

Countries

China

Contacts

Public ContactTan Qiwen
qiwentan@sdutcm.edu.cn+86 13793188118

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026