Subthreshold Depression
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for subthreshold depression; 2. Aged between 18-60 years, and the gender is not limited; 3. Hamilton-17-item Depression Scale (HAMD-17) score: 7 points <= HAMD <17 points; 4. Have not used any antidepressant drugs for at least 2 weeks before treatment, and have not received acupuncture treatment for depression in the past 3 months; 5. It is forbidden to take antibiotics, probiotics and fermented dairy products such as yogurt before entering the group and providing specimens; 6. Be able to actively cooperate with the treatment and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with clinically diagnosed depression, previous mental illness or organic mental disorder; 2. Those with severe liver and kidney damage, severe arrhythmia or cardiac insufficiency; 3. Pregnant and lactating patients; 4. Depressive episodes caused by psychoactive substances or non-addictive substances; 5. The patient has a strong suicide attempt or behavior; 6. Those who cannot tolerate acupuncture treatment; 7. Those who have communication difficulties or do not cooperate with the researcher; 8. Other situations judged by the investigator to be inappropriate for inclusion in the observation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hamilton depression scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Generalized anxiety scale;The proportion of people who developed moderate depression;9 items of patient health questionnaire;Quality of life scale SF12 2nd edition; | — |
Countries
China