Alzheimer's disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Meet the DSM-IV-R diagnostic criteria for dementia; 2. Meet the diagnostic criteria for probable AD in the NIA-AA criteria; 3. Aged 50 to 85 years; 4. Clinical dementia assessment score >= 0.5 points, MMSE score =3 hours a day, >=3 days a week) sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Accompanied by severe cerebrovascular disease; 2. Associated with other neurological or non-neurological diseases that can cause cognitive dysfunction or progressive memory impairment; 3. Drug-induced cognitive dysfunction or progressive memory impairment; 4. Inpatient or moderately high dependency nursing facility; 5. Patients with severe fear of needles, fainting of needles, and severe skin infections; 6. Patients with severe cardiovascular disease, malignant tumor, severe liver and kidney insufficiency; 7. Currently participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinician Interview–Based Impression of Change scale;Neuropsychiatric Inventory;Alzheimer disease assessment scale cognition; | — |
Secondary
| Measure | Time frame |
|---|---|
| Activity of Daily Living Scale; | — |
Countries
China
Contacts
Guang'anmen Hospital, China Academy of Chinese Medicine Sciences