depression
Conditions
Interventions
healthy control group:Nil
Sponsors
Beijing Hospital of Traditional Chinese Medicine, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnosis of mild-to-moderate depression according to the International Classification of Diseases 10th Edition (ICD-10, F32.0, F32.1); 2. Aged from 18 to 45 years, and right handed; 3. First diagnosed, have not participated in other treatment plans; 4. 24-item Hamilton Depression Scale total score<=35; 5. Signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Diagnosis of bipolar depression; 2. Have participated in other clinical trials in the past eight weeks; 3. Be taking antidepressants or the pharmacological effects of antidepressants have not been washed out; 4. Have received acupuncture treatment in the past two weeks; 5. Pregnant or lactating; 6. Have other serious diseases that needed to be treated; 7. Have head trauma history or other brain diseases; 8. Have suicidal plan or behavior; 9. Have any MRI contraindications.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24-item Hamilton depression scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| resting-state fMRI;diffusion tensor imaging;gray matter volume and cortical thickness;Quick inventory of depressive symptomatology-self report; | — |
Countries
China
Contacts
Public ContactZhao Bingcong
Department of Acupuncture and Moxibustion, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University
Outcome results
None listed