Rheumatoid arthritis with interstitial pneumonia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Comply with 2010 ACR/EULAR RA classification standard and RA-ILD (UIP type) diagnosis; 2. 5.1> DAS28 >2.6; 3. Course of disease> 24 months; 4. Aged from 18 to 65 years; 5. The patient informed and agreed to participate in the study.
Exclusion criteria
Exclusion criteria: 1. Those who have used DMARDs other than hydroxychloroquine and glucocorticoids within 2 months; 2. Patients with other severe organ disease or mental illness; 3. Those who are allergic to the drugs involved in the research protocol or have contraindications.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Carbon monoxide dispersion capacity;Forced vital capacity;ILD score on HRCT scan; | — |
Secondary
| Measure | Time frame |
|---|---|
| Overall assessment of the patient's own condition PGA;Functional Assessment of Treatment of Chronic Diseases-Fatigue;Doctor's overall assessment of the patient's condition MDGA;Clinical disease activity index score;Simplified disease activity index score;Rheumatoid arthritis disease activity evaluation index DAS28;Health Assessment Questionnaire Disability Index HAQ-DI; | — |
Countries
China
Contacts
Zhejiang Chinese Medical University