Multi-modal MRI and artificial intelligence to explore the brain-gut interaction of functional constipation and the clinical study of integrated traditional Chinese and western medicine treatment

Multi-modal MRI and artificial intelligence to explore the brain-gut interaction of functional constipation and integrated traditional Chinese and western medicine treatment

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ITMCTR

Registry ID

ITMCTR2100005047

Enrollment

Unknown

Registered

2021-07-12

Start date

2021-07-01

Completion date

Unknown

Last updated

2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

functional constipation

Interventions

Control group:Traditional Chinese medicine (decontamination decoction as the main prescription) + false magnetic stimulation

Experimental group:Traditional Chinese medicine + repeated transcranial magnetic stimulation

Eligibility

Sex/Gender

All

Age

19 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.The Roman IV diagnostic criteria for chronic constipation; 2.Above the age of 18; 3.Right-handed; 4.Signed the informed consent and volunteered to participate in the study.

Exclusion criteria

Exclusion criteria: 1.Constipation caused by anal stenosis caused by organic lesions of the digestive tract; 2.Pregnancy, previous history of serious cardiovascular disease, epilepsy, craniocerebral surgery, mental illness, etc.; 3.Patients with head metal foreign body, cardiac pacemaker and other magnetic resonance examination contraindication. 4.People with allergies, such as allergies to two or more drugs or food; Or known allergy to the ingredients of this medicine.

Design outcomes

Primary

Measure	Time frame
Bristol Stool Scale;Constipation severity score;	—

Secondary

Measure	Time frame
Depression score;Anxiety score;	—

Countries

China

Contacts

Public ContactQian Haihua

Jiangsu Provincial Hospital of TCM

haihuaqian@126.com+86 13851949998

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026