Diabetic Lower Extremity Atherosclerotic Disease
Conditions
Interventions
Sponsors
Guangdong Provincial Hospital of Chinese Medicine
Eligibility
Sex/Gender
All
Age
35 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for diabetes, and meet the diagnosis of type 2 diabetes; 2. Meet the LEAD diagnostic criteria; 3. The LEAD stage belongs to the Fontaine stage i; 4. Aged 35 to 70 years, gender is not limited; 5. Those who have started hypoglycemic, antihypertensive, and lipid-lowering western medicine treatment, and those who have been using the medicines stably for more than 3 months. 6. Willing to obey the doctor's treatment plan and cooperate with follow-up.
Exclusion criteria
Exclusion criteria: 1. Psychiatric patients who cannot understand the nature and scope of the research or who cannot comply with the doctor's orders; 2. Ulcers or gangrene on the skin of the lower extremities, moderate to severe edema of the lower extremities, or skin diseases; 3. Patients with acute complications such as diabetic ketoacidosis, hyperglycemia and hyperosmolar syndrome, and diabetic lactic acidosis; 4. Patients with malignant tumors, those with severe heart, liver, and kidney dysfunction, and those with a history of cardiovascular and cerebrovascular diseases such as stroke or myocardial infarction; 5. Patients with various blood diseases and bleeding tendency, such as thrombocytopenia, leukemia, hematemesis, hematemesis, blood in the stool, hematuria, hemoptysis, cerebral hemorrhage, and severe open injuries such as acute gastrointestinal perforation; 6. Those who are pregnant or breastfeeding; 7. Allergic constitution or those who have ever been allergic to the components of the drug in this study, who need to take antiplatelet, anticoagulant, and vasodilator drugs for a long time due to the disease; 8. Those who are participating in other similar interventions; 9. Combined with other peripheral vascular diseases such as Takayasu arteritis, Raynaud's disease and thromboangiitis obliterans, hyperthyroidism, hyperthyroidism, long-term use of steroid hormones and other diseases that may have a significant impact on this study. drugs, etc.; 10. Patients with poor compliance may affect the efficacy and safety of the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ankle Brachial Index; | — |
Secondary
| Measure | Time frame |
|---|---|
| interleukin 6;European Five-Dimensional Health Scale;Peak systolic blood flow, tube diameter, and intimal thickness of dorsal foot artery;Blood lipids;Four items of endothelium ;serum tumor necrosis factor a;Skin temperature;Traditional Chinese Medicine Syndrome Points;Plasma viscosity;Whole blood viscosity;blood sugar;Fibrinogen;high-sensitivity C-reactive protein; | — |
Countries
China
Contacts
Public ContactFan Guanjie
Guangdong Provincial Hospital of Chinese Medicine
Outcome results
None listed