Diabetic Nephropathy
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. It also meets the syndrome differentiation criteria of Chinese medicine for thirst dissipating nephropathy (deficiency of both Qi and Yin combined with stasis and toxin), Western medicine diagnostic criteria for type 2 diabetes and diabetic nephropathy (stage IV). 2. Aged 18 to 70 years,Male or Female; 3. Fasting blood glucose was less than 11.0mmol/L and 2h postprandial blood glucose was less than 15mmol/L;HbA1c does not exceed 8.0%; 4. GFR > 60ml/min and 24-hour urinary protein quantification < 5.0g/24h, systolic blood pressure is controlled in 140-90mmHg, diastolic blood pressure is controlled in 90-60mmHg; 5. Patients were informed and voluntarily participated in the experimental study and signed the consent form, showing good compliance.
Exclusion criteria
Exclusion criteria: 1. Suffering from mental disorders who are unable to cooperate with treatment and cannot follow the medical advice and receive treatment on time; 2. With recent acute complications and combined infection; 3. Women who are pregnant, lactating or preparing to become pregnant, or who are allergic to the drug used in the test; 4. Have received hemodialysis and kidney transplantation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glycosylated hemoglobin; Urinary protein quantification;Scr;FBG(fasting blood-glucose);Glomerular filtration rate;Symptom score;Proteomics;PBG(FBG(fasting blood-glucose));Metabonomics; | — |
Secondary
| Measure | Time frame |
|---|---|
| Total cholesterol;LDL;HDL;Triglyceride; | — |
Countries
China
Contacts
Changchun University of Chinese Medicine