Taking placebo as the control, to evaluate the randomized, double-blind, double-blind, randomized, double-blind, randomized, double-blind, randomized, double-blind, evaluation of the early intervention of Qingjie Xuantou Feiwei Recipe (Yinhua Pinggan Granules) in the early and mid-stage of community-acquired drug-resistant bacterial pneumonia

Study on the Effect and Mechanism of Qingjie Xuantou Feiwei Recipe (Yinhua Pinggan Granules) and Its Components in Interfering with Severe Disease of Drug-resistant Bacterial Pneumonia

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ITMCTR

Registry ID

ITMCTR2100004958

Enrollment

Unknown

Registered

2021-06-20

Start date

2021-06-30

Completion date

Unknown

Last updated

2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bacterial pneumonia

Interventions

Group A:Western medicine basic treatment + Yinhua Pinggan granules (YYPG), po, 6g/time, bid.

Group B:Western medicine basic treatment + traditional Chinese medicine placebo, po, 6g/time, bid.

Eligibility

Sex/Gender

All

Age

18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria for community-acquired pneumonia; 2. TCM syndrome differentiation is the syndrome of evil-stagnation lung health or phlegm-heat obstructing the lung syndrome (pneumonia is mild and moderate, the syndrome belongs to Wei-Qifen syndrome); 3. Voluntarily participate, understand and sign the informed consent; 4. Aged 18 to 85 years.

Exclusion criteria

Exclusion criteria: 1. Cannot follow the treatment; 2. Patients with severe heart and brain diseases; 3. Those who are allergic to western medicine and traditional Chinese medicine; 4. Have used traditional Chinese medicine to treat patients; 5. Multi-drug resistant persons.

Design outcomes

Primary

Measure	Time frame
Pneumonia cure rate;	—

Secondary

Measure	Time frame
Lactic acid (LC), procalcitonin (PCT), oxygenation index (PaO2/FiO2);Bacterial clearance rate and LC clearance rate of lower respiratory tract;Critical degree score (SMART-COP score);Body temperature, CRP;Conversion rate of severe pneumonia;Acute physiology and chronic health assessment system (APACHEII score);TCM symptom score;	—

Countries

China

Contacts

Public ContactWan Haitong

Zhejiang Chinese Medical University

whtong@126.com+86 13606614920

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026