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A Clinical Efficacy Prediction Study of Acupuncture treatment for Migraine Based on Multimodal Neuroimaging Technology and Gene Polymorphism

A Clinical Efficacy Prediction Study of Acupuncture treatment for Migraine Based on Neuroimage and COMT Gene Polymorphism

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2100004847
Enrollment
Unknown
Registered
2021-01-31
Start date
2021-02-22
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Migraine

Interventions

Sponsors

Chengdu University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Aged from 18 to 65 years; 2.Migraine without aura patients: meetting the ICHD-3 2018 edition diagnostic criteria for migraine (without aura) published by the International Headache Society; 3.Tension-type headache patients: meetting the ICHD-3 2018 edition diagnostic criteria for primary tension-type headache published by the International Headache Society; 4.Right handedness; 5.With a history of migraine or tension-type headache for over 6 months; 6.Migraine or tension-type headache attacks more than once a month in the past 3 months; 7.Did not receive no acupuncture treatment in the past 3 months; 8.Did not take any preventive, long-acting analgesics, psychotropic drugs (such as Prozac and estazolam eurodin) or vasoactive drugs for migraine or tension-type headache in the past 3 months; 9.The informed consent is signed by the patient himself or his immediate family member. Note: Only those who meet each of the above 9 criteria can be included in the study.

Exclusion criteria

Exclusion criteria: 1.Suffering from other pain conditions; 2.Suffering from mental disorders (such as primary anxiety, primary depression, schizophrenia, etc.); 3.Suffering from cognitive and consciousness disorder who cannot comply with the experiment procedure; 4.Suffering from cancer, circulation, phumalnory, urinary, hematopoietic and other systems serious primary diseases; 5.Being pregnant or lactating; 6.Patients who have a history of alcohol or drug abuse or drug addiction; 7.Having acupuncture contradictions; 8.Having MRI contraindications (such as there are metal implants in the body, or suffer from claustrophobia syndrome, etc.). Note: Those who meet any of the above 8 criteria should be excluded in the study.

Design outcomes

Primary

MeasureTime frame
Number of headache days;Number of headache attacks;

Secondary

MeasureTime frame
The use of non-steroidal drug;Emotion-related scale;Average VAS scores for headaches;Effective rate;

Countries

China

Contacts

Public ContactLi Zhengjie

Acupuncture and Tuina School/The 3rd Teaching Hospital, Chengdu University of Traditional Chinese Medicine

lzjbenjamin@163.com+86 18215675610

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026