Post stroke depression
Conditions
Interventions
Sponsors
The First Affiliated Hospital of Dalian Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Refer to the "Key Points for Diagnosis of Various Cerebrovascular Diseases" revised by the Chinese Medical Association to be diagnosed with stroke; 2. According to the "Chinese Classification and Diagnosis of Mental Disorders-Third Edition" (CCMD-III), subjects diagnosed with secondary mild to moderate depression, Hamilton Depression Scale (HAMD-17) 17 items Score between 7 and 24 points; 3. The age of the subject is between 40 and 80 years old, regardless of gender; 4. Patients who were diagnosed with depression for the first time after stroke (diagnosed as PSD within 6 months after stroke); 5. No history of mental illness or family history of mental illness before stroke; 6. Normal consciousness can cooperate with various examinations, no aphasia or severe cognitive impairment, mental status examination (MMSE score)> 17 points; 7. Liver and kidney function tests are normal; 8. Be able to provide a voluntary signed informed consent form.
Exclusion criteria
Exclusion criteria: 1. Participate in any other clinical trials or take hormones and psychotropic drugs within the last 1 month; 2. Unstable vital signs, poor control of underlying diseases, or serious systemic diseases such as heart disease or malignant tumors; 3. Allergic to the ingredients of Kaixin Changyu Granules; 4. Pregnant or lactating women; 5. Magnetic resonance contraindications.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Homocysteine;High sensitivity C-reactive protein;Related scales;FA value of DTI; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of adverse reactions; | — |
Countries
china
Contacts
Public ContactLiu Yong
The First Affiliated Hospital of Dalian Medical University
Outcome results
None listed