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Acupuncture and Chinese herb medicine Yangjing Zhongyu Decoction for the treatment of endometriosis-associated infertility: a multi-center, controlled and randomized clinical trial

Study on the curative effect of acupuncture combined with traditional Chinese medicine in the treatment of endometriosis-associated infertility

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2100004830
Enrollment
Unknown
Registered
2021-01-29
Start date
2021-01-15
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

endometriosis-associated infertility

Interventions

Sponsors

Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1.Women aged between 21 and 45 years with fertility intention; 2.Patients who meet the diagnostic criteria for both endometriosis and infertility; a. Endometriosis: histopathological results: endometrial glands and stroma found in the lesion, accompanied by inflammation and fibrosis. b. Infertility: women who fail to achieve a clinical pregnancy after 12 months or more of regular unprotected sexual intercourse; this includes secondary infertility which is a failure to conceive after a previous pregnancy. 3.Patients who have accepted the treatment of laparoscopic conservative operation; 4.Husbands semen analysis is normal; 5.Willingness to sign the consent form.

Exclusion criteria

Exclusion criteria: 1.Those who have other infertility factors (such as PCOS, tubal blockage, immune infertility, reproductive malignant tumor, reproductive organ abnormalities, and so on); 2.Those who have used other drugs that affect reproductive function or metabolism in the past 3 months; 3.Those who are not appropriate for acupuncture; 4.Those who have allergies to Chinese herbs or GnRH-a; 5.Patients with serious cardiovascular, liver, kidney, and hematopoietic system diseases; 6.Patients with infectious diseases, mental illness, and other medical histories.

Design outcomes

Primary

MeasureTime frame
HCG;gestational sac;

Secondary

MeasureTime frame
AMH;CA125;ALT;sex hormones;Ultrasound findings;endometriosis-specific quality of life;

Countries

China

Contacts

Public ContactZhang Chunyan

Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine

zh_ch_yan@163.com+86 15921068889

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026