Premature ovarian insufficiency
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Female patients aged between 25-40, 2. Haven't received any other treatments in the last two months before enrollment; 3. No pregnancy plan in six months; 4. Patients voluntarily participate in the study; 5. Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Those who are pregnant; 2. Patients with primary amenorrhea; 3. Congenital reproductive organ abnormalities; 4. Patients with internal diseases which can affect reproductive hormones, such as thyroid disease, SLE, etc.; 5. Patients with other serious internal diseases and mental diseases; 6. Patients with unilateral or bilateral oophorectomy; 7. Those who are unable to tolerate the tests or treatments during the course of this study; 8. Those who are participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum Anti Mullerian Hormone, AMH;Follicle Stimulating Hormone, FSH; | — |
Secondary
| Measure | Time frame |
|---|---|
| Menstrual condition;Follicle Stimulating Hormone/Luteinizing hormone , FSH/LH;Serum estradiol, E2;Kupperman index;Luteinizing hormone, LH; | — |
Countries
China
Contacts
The Third Affiliated Hospital of Zhejiang Chinese Medical University