Septic Cardiomyopathy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Meet the diagnostic criteria of septic cardiomyopathy; 2.TCM syndrome differentiation meets the diagnostic criteria of cardiopulmonary qi deficiency and (or) heart and kidney yang deficiency and (or) yang deficiency and water flooding syndrome; 3.Aged between 18-80 years old; 4.Patients Or family members signed an informed consent form.
Exclusion criteria
Exclusion criteria: 1.ICU hospitalization time is less than 3 days; 2.History of serious underlying heart diseases; 3.Patients with advanced tumor; 4.Patients with primary liver, kidney, and blood system with serious underlying diseases; 5.Contraindications to enteral nutrition; 6.Patients with immunodeficiency; 7.Intestinal Nutritional contraindications; 8.Pregnant and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Immunological indicators (peripheral blood HLA-DR, CD4+T lymphocytes, CD8+T lymphocytes, natural killer cells, regulatory T cells, helper T cells 17, interleukin-10, immunoglobulin IgG, IgM) ;Serum markers of myocardial injury (cardiac troponin, creatine kinase isoenzyme, cardiac fatty acid binding protein, amino-terminal brain natriuretic peptide precursor); | — |
Secondary
| Measure | Time frame |
|---|---|
| Multiple organ dysfunction score;Serum inflammatory cytokines (interleukin-6, procalcitonin, c-reactive protein);Acute physiology and chronic health score;ICU hospital stay;28-day mortality;Clinical symptom score; | — |
Countries
China
Contacts
Beijing University of Chinese Medicine Shenzhen Hospital (Longgang)