Graves Disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged between 18 and 65 years; 2. According to the diagnostic criteria of Graves disease who diagnosed with Graves disease and with goiter; 3. Who have signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with thyrotoxicosis caused by causes other than Graves' disease, such as nodular toxic goiter and autonomous high-functioning thyroid adenoma; 2. Patients with active thyroid eye disease; 3. Patients with thyroid cancer and other malignant tumors; 4. Patients with abnormal liver and kidney function (ALT or AST > 2 times the upper limit of normal, Scr > upper limit of normal) and other serious diseases of the system; 5. Patients with a history of radioactive 131I or surgical treatment; 6. Women with pregnancy or lactation; 7. Have used antithyroid drugs or other drugs that may affect this test in the past two weeks; 8. Patients with hyperthyroidism crisis or hyperthyroidism with myasthenia gravis; 9. Those who are known to be allergic to the test drug or its components; 10. Researchers consider that they are not suitable for selection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PA;TSH;FT3;FT4;Alb; | — |
Secondary
| Measure | Time frame |
|---|---|
| TGAb;TRAb;Goiter scale;TPOAb; | — |
Countries
China
Contacts
Guang'anmen Hospital, China Academy of Chinese Medical Sciences