Cough Variant Asthma
Conditions
Interventions
Sponsors
Affiliated Hospital of Changchun University of traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
4 Years to 7 Years
Inclusion criteria
Inclusion criteria: 1. Diagnostic criteria of Western medicine: (1) Cough lasted for more than 4 weeks, often in the night and (or) morning attack or aggravation, mainly dry cough. (2) There was no sign of infection in clinic, or it was ineffective after a long time of antibiotic treatment. (3) The diagnostic treatment of antiasthmatic drugs is effective. (4) Other causes of chronic cough were excluded. (5) Bronchial provocation test positive and / or PEF diurnal variation rate (continuous monitoring for 2 weeks) were continuously monitored. (6) A history of atopic disease or positive allergen test in individuals or first or second degree relatives. The above items (1)-(4) are the basic conditions for diagnosis. 2. TCM diagnostic criteria: Syndrome of wind cold attacking lung Main symptoms: cough, paroxysmal cough, less or no phlegm, obvious in the night and morning. Secondary symptoms: pharyngeal itching, light tongue, or runny nose, thin and white fur, light purple sublingual collaterals, purplish air pool under the eyes, reddish and slightly swollen turbinate turbinate, and tight pulse. 3. The age is between 4 and 7 years old; 4. The subjects and their guardians voluntarily participated in the clinical trial and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Chronic cough caused by other reasons; 2. Glucocorticoids, leukotriene modulators, long-acting ß 2 receptor agonists and theophylline were used in the two weeks before enrollment; 3. Allergy to the test drug or some components of the drug; 4. Combined with other serious diseases of the system; 5. Participated in other drug trials within 3 months before the test; 6. Other factors considered by the researcher as unsuitable for participation in this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TCM syndrome score;Daily mean score of cough severity; | — |
Countries
China
Contacts
Public ContactXiaochun Feng
Affiliated Hospital of Changchun University of Traditional Chinese Medicine
Outcome results
None listed