allergic rhinitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria All the following conditions should be met for the included patients: (1) Those who met the diagnostic criteria of moderate to severe persistent allergic rhinitis; (2) According to the international diagnostic criteria (ARIA) of AR: ? Clinical symptoms: two or more symptoms such as sneezing, clear water like runny nose, nasal itching and nasal congestion, lasting or accumulating for more than 1 hour every day; ? Allergen test: at least one allergen SPT and / or serum specific IgE were positive. (3) The TNSS score should be = 4. (4) They were 18-65 years old; (5) Informed consent, signed informed consent form, and volunteers.
Exclusion criteria
Exclusion criteria: Exclusion criteria Those with one of the following conditions will be excluded from this study: (1) Patients with acute sinusitis or respiratory tract infection in the past two weeks; (2) Patients with bronchial asthma, moderate or above atopic dermatitis, immune diseases and severe chronic inflammatory diseases; (3) History of drug allergy; (4) Those who have received specific immunotherapy in the past two years, and those who have received anti allergic Chinese medicine, systemic hormone therapy or antihistamine therapy in the past two weeks; (5) Pregnant or lactating patients. (6) Severe lung, liver, kidney disease or other serious primary disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total nasal symptom scale (TNSS); | — |
Secondary
| Measure | Time frame |
|---|---|
| Rhinitis Quality of Life Questionnaire, RQLQ;Detection of serum specific IgE level; | — |
Countries
China