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Clinical study on the treatment of allergic rhinitis with Chinese herbal medicine desensitization Zhixiao Decoction: a randomized controlled trial

Clinical study on the treatment of allergic rhinitis with Chinese herbal medicine desensitization Zhixiao Decoction: a randomized controlled trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2100004670
Enrollment
Unknown
Registered
2021-03-30
Start date
2021-04-01
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

allergic rhinitis

Interventions

Chinese medicine placebo group:Oral administration of desensitization Zhixiao Decoction placebo
Chinese medicine treatment group:Oral administration of traditional Chinese Medicine

Sponsors

Shanghai Dongfang Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria All the following conditions should be met for the included patients: (1) Those who met the diagnostic criteria of moderate to severe persistent allergic rhinitis; (2) According to the international diagnostic criteria (ARIA) of AR: ? Clinical symptoms: two or more symptoms such as sneezing, clear water like runny nose, nasal itching and nasal congestion, lasting or accumulating for more than 1 hour every day; ? Allergen test: at least one allergen SPT and / or serum specific IgE were positive. (3) The TNSS score should be = 4. (4) They were 18-65 years old; (5) Informed consent, signed informed consent form, and volunteers.

Exclusion criteria

Exclusion criteria: Exclusion criteria Those with one of the following conditions will be excluded from this study: (1) Patients with acute sinusitis or respiratory tract infection in the past two weeks; (2) Patients with bronchial asthma, moderate or above atopic dermatitis, immune diseases and severe chronic inflammatory diseases; (3) History of drug allergy; (4) Those who have received specific immunotherapy in the past two years, and those who have received anti allergic Chinese medicine, systemic hormone therapy or antihistamine therapy in the past two weeks; (5) Pregnant or lactating patients. (6) Severe lung, liver, kidney disease or other serious primary disease.

Design outcomes

Primary

MeasureTime frame
Total nasal symptom scale (TNSS);

Secondary

MeasureTime frame
Rhinitis Quality of Life Questionnaire, RQLQ;Detection of serum specific IgE level;

Countries

China

Contacts

Public ContactWang Qi
doctorwang2009@126.com15201229912

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026