Acute Ischemic Stroke
Conditions
Interventions
control group:conventional therapy
Sponsors
The Affiliated Hospital to Changchun University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Subjects who meet the diagnostic criteria of ischemic stroke in Chinese guidelines for diagnosis and treatment of acute ischemic stroke 2018. 2. Subjects meeting the diagnostic criteria of ischemic stroke. 3. Subjects within 2 weeks of acute onset of ischemic stroke. 4. Subjects with NIHSS score 4-20. 5. Subjects aged 40-80 years.
Exclusion criteria
Exclusion criteria: 1. Subjects diagnosed as hemorrhage or other pathological brain diseases according to head CT or MRI; 2. Subjects with allergic constitution and allergic to the test drug or its related taste or ingredients; 3. Patients with diabetes, whose blood glucose was less than 2.8 mmol / L or more than 16.7 mmol / L after using hypoglycemic drugs, or complicated with diabetic complications; 4. The ALT or AST levels of the subjects with severe liver damage were higher than the normal value of 1.5; 5. In the subjects with severe renal impairment, the CR level was 1.5 times higher than the normal value; 6. Patients with severe cardiac insufficiency, cardiac insufficiency or cardiac function rating above grade III; 7. Patients with cerebral embolism caused by brain tumor, brain trauma, brain parasitic disease, rheumatic heart disease, coronary heart disease and other heart diseases complicated with atrial fibrillation; 8. Disabled patients (blind, deaf, mute, mental retardation, mental retardation and limb disability caused by other reasons that affect the assessment of neurological deficit) stipulated by law; 9. Limb limitation caused by other diseases that affect the assessment of neurological deficit; 10. Subjects with bleeding tendency or severe bleeding within 3 months; 11. Subjects who suspected or had a history of alcohol or drug abuse, or who, according to the judgment of the researcher, had other circumstances that reduced or complicated the possibility of enrollment; 12. Women in menstrual period, pregnant women and lactating women, positive pregnancy test or recent fertility planning; 13. The subjects who have participated in other clinical trials for more than 3 months have not finished.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MRs; | — |
Secondary
| Measure | Time frame |
|---|---|
| NIHSS;Stroke syndrome elements evaluation scale;Barthel index; | — |
Countries
China
Contacts
Public ContactWang Yue
The Affiliated Hospital to Changchun University of Chinese Medicine
Outcome results
None listed