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Study on the characteristic spectrum of sleep related factors in patients with insomnia diagnosed by single chief complaint of Wushen type

Study on the characteristic spectrum of sleep related factors in patients with insomnia diagnosed by single chief complaint of Wushen type

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ITMCTR
Registry ID
ITMCTR2100004655
Enrollment
Unknown
Registered
2021-01-09
Start date
2021-01-31
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

insomnia

Interventions

Sponsors

Ttraditional Chinese Medicine Hospital of Xinjiang Uygur Autonomous Region
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Inclusion criteria of healthy control (the following four items should be met simultaneously): (1) They are between 20 and 60 years old, including those aged 20 and 60 years. (2) Healthy without disease. (3) The age, gender and ethnic characteristics of the patients were the same as those of the other groups. (4) Informed consent, volunteers, signed informed consent. 2. The inclusion criteria of TCM insomnia five spirit classification (the following five items should be met at the same time): (1) All the cases met the diagnostic criteria of traditional Chinese and Western Medicine (see above). (2) Pittsburgh sleep quality index (PSQI) score >= 8. (3) They are between 20 and 60 years old, including those aged 20 and 60 years. (4) The six groups were comparable in age, gender and ethnic characteristics. (5) Informed consent, volunteers, signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Exclusion criteria for healthy control: those who conceal their health, age, gender and voluntary status. 2. Exclusion criteria for the study of insomnia five spirit classification in traditional Chinese Medicine (1) Among the five types of chief complaint symptoms, it is difficult to select the single chief complaint symptom or the single chief complaint symptom is not prominent. (2) Pregnant and lactating women. (3) Insomnia caused by drinking and taking central stimulant drugs. (4) Insomnia caused by physical and mental diseases. (5) Use of psychotropic drugs or not discontinued for more than two weeks (6) Heart, brain, kidney, liver and other serious diseases.. (7) Patients with epilepsy. (8) Poor compliance of scientific research and incomplete data.

Design outcomes

Primary

MeasureTime frame
Corticotropin releasing hormone;GABA;leptin;Adrenocorticotropic hormone;T3;Norepinephrine;IL-6;histamine;5-hydroxyindoleacetic acid;melatonin;GAD;IL=1;glycine;Hydrocortisone;T4;testosterone;VIP;acetylcholine;DA;glutamate;Gonadotropin releasing hormone;Thyroid stimulating hormone releasing hormone;5-HT;Estradiol;Apolipoprotein;Orexin A;

Countries

China

Contacts

Public ContactZhang Xingping

Xinjiang Medical University

xjzyzxp@xjmu.edu.cn+86 991-5855139

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026