schizophrenia
Conditions
Interventions
Sponsors
Hangzhou Seventh Peoples Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1.ICD-10 diagnostic criteria for schizophrenia, schizoid psychosis or schizoaffective disorder; Hospitalized or outpatient patients; 2. No gender limitation, aged 18 to 40 years; 3.(1)The first attack, the course of disease is not more than 2 years; (2)The duration of continuous treatment for never taking medication or taking the same antipsychotic medication is <2 weeks, and the cumulative duration of antipsychotic exposure is <6 weeks.; 4. Able to complete questionnaires under the guidance of clinical researchers, use APP, agree to informed consent and participate voluntarily; 5. Body mass index (BMI) is not less than 17.0kg/m2; 6. No language or hearing impairment.
Exclusion criteria
Exclusion criteria: 1. Disease is not the diagnosis of schizophrenia, such as dissociation disorder, bipolar disorder, depression, schizoaffective disorder, etc.; 2. In the 6 months before screening, active substance dependence (excluding nicotine and caffeine dependence) was diagnosed; 3. Patients with a severe tendency to suicide within 12 months prior to screening or violence as clinically assessed during the screening; 4. Past or present suffering from any serious or unstable cardiovascular, respiratory, neurological (including epilepsy or major cerebrovascular), kidney, liver, blood, uncontrolled diabetes, glaucoma, or other system diseases. Coma, delirium, mild-to-moderate or severe mental retardation, there can result in long QT, ventricular tachycardia or sudden death risk factors; 5. The results of blood routine, biochemical, hematological and electrocardiogram examinations are not within the normal range of laboratory values and have clinical significance as judged by researchers; 6. Evidence of liver disease at the time of prior or screening; 7. Previous neuroblocker malignant syndrome (NMS) or tardive dyskinesia; 8. Women who are pregnant, breastfeeding or who plan to become pregnant within 6 months; 9. Patients with previous mental retardation or mental retardation; 10. Participated in other clinical studies within 30 days before screening.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| blood routine examination;routine urine test;hepatorenal function;electrocardiograph; | — |
Countries
China
Contacts
Public ContactZhang Lina
Hangzhou Seventh Peoples Hospital
Outcome results
None listed