Psoriasis Vulgaris With Overweight/Obesity
Conditions
Interventions
Sponsors
Guangdong Provincial Hospital of Chinese Medicine/The Second Affiliated Hospital of Guangzhou University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. The patient meets the diagnostic criteria of western medicine for psoriasis vulgaris and the diagnostic criteria of spleen deficiency dampness and blood stasis syndrome in Traditional Chinese Medicine; 2. The condition of patients is in a stationary phase; 3. PASI 1 to 10 and BSA =24 (kg/m2) or waist circumference: male >= 90cm, female >= 85cm; 5. Aged 18 to 65 years old; 6. Patients who voluntarily participate in the study and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Articular, pustular, erythrodermal, drip, progressive psoriasis and psoriasis in specific sites, including face, scalp, fingernails, folds, glans, and palmoplantar; 2. Secondary overweight or obesity caused by hypothyroidism, polycystic ovary syndrome, insulinoma, hypercortisolism and drugs; 3. Women who are pregnant, lactating, or planning to become pregnant during the study period; 4. Patients with severe primary diseases such as circulatory, respiratory, digestive , urinary, endocrine and hematopoietic system, which cannot be controlled by conventional medication, patients with diabetes or tumor, and patients with severe infection, water, electrolyte and acid-base balance disorders. Or patients whose clinical test indicators is one of the following conditions: The increase of alanine aminotransferase or aspartate aminotransferase > 1.5 ULN; the increase of creatinine > 1.5 ULN; the increase of hemoglobin > 20g/L of ULN; the decrease of platelet count 5.5mmol/L or the decrease of blood potassium 50 or SDS > 53, or combined with other mental diseases; 10. Other conditions that the investigator deems inappropriate for participation in the study.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Physician's Global Assessment;Waist Circumference;Body Weight;Body Mass Index;Waist-to-Hip Ratio;Response rate of PASI 90;Impact of Weight on Quality of Life-Lite;Dermatology Life Quality Index;Psoriasis Area and Severity Index;Visual Analog Scale;Response rate of PASI 75;Hip Crcumference;Psoriasis Vulgaris Symptoms Scale; | — |
Primary
| Measure | Time frame |
|---|---|
| Response rate of PASI 50; | — |
Countries
China
Contacts
Public ContactChuan-Jian Lu
Guangdong Provincial Hospital of Chinese Medicine/The Second Affiliated Hospital of Guangzhou University of Chinese Medicine
Outcome results
None listed