Cardiac neurosis (Hessian palpitations)
Conditions
Interventions
Sponsors
Fuwai Hospital, Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged >= 18 and <=75 years; 2. It meets the diagnostic criteria of cardiac neurosis: the patient has heart palpitations, precardiac pain, chest shortness of breath, dyspnea, dizziness, insomnia and dreaminess, hand and foot chills, sweating and other cardiovascular symptoms and neurological disorders; 3. It meets the diagnostic criteria of Mongolian medicine Heyisheng type palpitation; 4. No objective basis for the diagnosis of CHD (conforms to any of the following); (1) The movable plate test was negative; (2) Coronary angiography or coronary CTA indicated lumen stenosis <= 50%; (3) No myocardial ischemia was found by exercise or drug stress radionuclide examination. 5. Patients did not take anti-anxiety and depression drugs or psychotropic drugs within 2 weeks before enrollment; 6. Signed the informed consent.
Exclusion criteria
Exclusion criteria: (1) Patients with organic heart disease and severe cardiopulmonary insufficiency; (2) Poor hypertension control (post-treatment systolic blood pressure >= 160mmHg or diastolic blood pressure >= 100mmHg); (3) Patients with malignant arrhythmia; (4) Patients with cardiac pacemakers; (5) Patients with hyperthyroidism; (6) Severe hepatic and renal function impairment (ALT, AST or TBIL>2 times the upper normal reference value, or CR BBB>5 times the upper normal reference value); (7) Complicated with hematopoietic system and other serious primary diseases, mental illness; (8) SAS >= 70 points; (9) SDS >= 73 points; (10) Accompanied by any other serious disease or condition such as: malignant tumor; (11) Women in pregnancy or lactating period; (12) People with allergies or allergies to known ingredients of the study drug; (13) Participated in other clinical researchers within the last 3 months; (14) In the Investigator's judgment, the subjects were unsuitable for study observation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| At week 8, the proportion of patients with Heyshin type palpitation symptoms improved in Mongolian medicine; | — |
Secondary
| Measure | Time frame |
|---|---|
| SAS;Pittsburgh Sleep Scale score;Poor standing heart rate;serotonin;The frequency and dosage of the sedative and hypnotic drug serazepam;hs-crp;Incidence of adverse drug events and serious adverse events;SDS;Scores of the Evaluation Scale for the Symptom Classification of Heart Palpitations in Mongolian Medicine;Self-Rating Cardiac Neurosis Symptoms Scale ; | — |
Countries
China
Contacts
Public ContactLan Yue
Fuwai Hospital, Chinese Academy of Medical Sciences
Outcome results
None listed