Skip to content

Effect of acupuncture on the expression of tear inflammatory factors in patients with dry eyes

Effect of acupuncture on the expression of tear inflammatory factors in patients with dry eyes

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2100004584
Enrollment
Unknown
Registered
2021-03-17
Start date
2021-04-01
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dry eye

Interventions

Sponsors

The Eye Hospital of Wenzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Subjects must be between 18 and 65 years of age; 2. Diagnosed as a dry eye patient by BUT and Schirmer I test; 3. Participants must agree to participate in the trial, and both guardians and subjects must sign written informed consent; 4. Patients who have sufficient time to complete the trial study.

Exclusion criteria

Exclusion criteria: 1. Patients with other co-morbidities of the eye that affect the determination of efficacy; 2. Patients with Sjgren's syndrome and other rheumatological diseases; 3. Patients with thyroid-related eye disease and other systemic diseases that affect dry eye conditions; 4. Patients with other significant systemic organic pathologies such as hypertension, diabetes mellitus and renal disease; 5. Patients with depression, obsessive-compulsive disorder and other mental abnormalities; 6. Patients with combined blepharospasm; 7. Pregnant and breastfeeding or planning a pregnancy; 8. Patients who are participating in other clinical trials; 9. Patients who are afraid of acupuncture or have contraindications to acupuncture such as blood clotting disorders.

Design outcomes

Primary

MeasureTime frame
OSDI;BUT;Tear inflammatory factors (TNF-alpha, IL-1 beta, NLRP3, MUC5AC);

Secondary

MeasureTime frame
CFS;Schirmer I test;

Countries

China

Contacts

Public ContactShengjin Xiang

The Eye Hospital of Wenzhou Medical University

xiangsj@mail.eye.ac.cn+86 13758715162

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026