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Randomized double-blind controlled study of Qmaitongguan granule intervention on myocardial perfusion after acute myocardial infarction and reperfusion based on myocardial magnetic resonance technology

Randomized double-blind controlled study of Qmaitongguan granule intervention on myocardial perfusion after acute myocardial infarction and reperfusion based on myocardial magnetic resonance technology

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2100004575
Enrollment
Unknown
Registered
2020-12-28
Start date
2021-03-01
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute myocardial infarction

Interventions

Sponsors

The Second Affiliated Hospital of Guangzhou University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) With the diagnosis of ST-segment elevation acute myocardial infarction, PCI reperfusion therapy is performed within the time window; (2) Aged 18-75 years; (3) Volunteer to participate in this study and have signed an informed consent form; (4) Have a correct understanding of the significance of drug research, and have a good compliance with the observation and evaluation of researchers.

Exclusion criteria

Exclusion criteria: (1) Patients with severe cardiogenic shock at the time of inclusion; (2) Patients with suffered cardiac arrest before enrollment and had been undergoing cardiopulmonary resuscitation for a long time; (3) Patients with cardiac complications such as papillary muscle rupture and ventricular septal perforation; (4) Aortic dissection patients; (5) Patients with severe liver, kidney, nerve, and coagulation dysfunction; (6) Patients with severe infection; (7) Pregnant or lactating women; (8) Patients who participated in other Chinese medicine clinical studies within three months; (9) Those who are allergic to contrast media or the drug components of this study.

Design outcomes

Primary

MeasureTime frame
Myocardial rescue index;Myocardial structure function;

Secondary

MeasureTime frame
Seattle Angina Scale Score;NT-pro-BNP;6-minute walk test;TnT;Cystatin C;incidence of MACE;Echocardiography;Quality of Life Scale for Coronary Heart Disease with Integrated Traditional Chinese and Western Medicine and Scale for TCM Syndrome;High sensitivity C-reactive protein;CKMB;

Countries

China

Contacts

Public ContactMinzhou Zhang

The Second Affiliated Hospital of Guangzhou University of Chinese Medicine

minzhouzhang@aliyun.com+86 13924266368

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026