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Using resting-state functional magnetic resonance imaging to investigate a central mechanism of contralateral acupuncture at Hand-Yangming in patients with cerebral ischemic stroke

Using resting-state functional magnetic resonance imaging to investigate a central mechanism of contralateral acupuncture at Hand-Yangming in patients with cerebral ischemic stroke

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2100004539
Enrollment
Unknown
Registered
2021-03-06
Start date
2021-03-15
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebral ischemia stroke

Interventions

Control Group:Conventional acupuncture

Sponsors

Hospital of Chengdu University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) Corresponding to the diagnostic standards of cerebral ischemic stroke(Referring to the 2019 version cerebral vascular disease diagnostic criteria) and diagnosed with CIS and confirmed by CT or MRI, occurred >= 2 weeks and = 3 and < 10 or(and) the upper limbs function score of Brunnstrom stages recovery at the stage 1-5; (4) Aged between 35 and 75 years; (5) Informed consent signed by the patient or by the patient's relative; (6) Patients who have better compliance and can complete the research.

Exclusion criteria

Exclusion criteria: (1) Course of disease > 6 months, or advanced acute stroke, or unstable vital sign; (2) Persons with Wernicke's aphasia, severe cognitive impairment, mental illnesses or post-stroke depression. (3) Patients with severe heart, lung, liver, and kidney diseases; (4) Patients have pacemakers and metal implants in the body and underwent bypass operation or can't undergo MRI; (5) Persons with skin disease and coagulation dysfunction; (6) Pregnant women or women in puerperium; (7) Patients who can't cooperate with treatment, observation and examination. (8) Participants in other clinical tests at the same time.

Design outcomes

Primary

MeasureTime frame
R-fMRI;

Secondary

MeasureTime frame
Brunnstrom;NIH Stroke Scale scores;SS-QOL;Fugl-Meyer;MoCA;MBI;MMSE;

Countries

China

Contacts

Public ContactYaoguang Guo

Hospital of Chengdu University of Traditional Chinese Medicine

1035292848@qq.com+86 15928035811

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026