sepsis
Conditions
Interventions
control group:Nil
Sponsors
Beijing Friendship Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Adults >= 18 years old, meet SEPSIS 3.0 diagnostic criteria and have coagulopathy/early DIC. 1) Sepsis inclusion criteria, according to SEPSIS 3.0 diagnostic criteria. 2) Coagulation disorders/early DIC, refer to the International Society of Thrombosis and Hemostasis DIC scoring system (ISTH) for diagnosis. DIC scores of 3 to 4 are included.
Exclusion criteria
Exclusion criteria: 1) Pregnant or breastfeeding women; 2) Aged 650 mg/d or warfarin in the past 7 days, or have undergone thrombolytic therapy in the past 1 month; 12) the patient is dying (estimated Died within 6 hours); 13) Known or suspected brain death; 14) Is undergoing dialysis treatment; 15) The patient is undergoing other treatment studies that may interfere with this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| platelet;D-Dimer;Thymidine phosphorylase;HMGB1;PT;Fibrinogen; | — |
Secondary
| Measure | Time frame |
|---|---|
| Creatinine;Aspartate aminotransferase;AT III;Bilirubin;Procalcitonin;Heparin binding protein;Interleukin 10;Alanine aminotransferase; | — |
Countries
China
Contacts
Public ContactQi Wenjie
Beijing Friendship Hospital, Capital Medical University
Outcome results
None listed