ankylosing spondylitis
Conditions
Sponsors
The Affiliated Jiangnan Hospital of Zhejiang Chinese Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Participants meeting the following requirement will be included. (1) It is in accordance with as New York standard revised by American Society of Rheumatology in 1984; (2) The diagnosis was in accordance with the New York criteria revised in 1984; The Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) was used to indicate the disease activity when the score was more than 4. (3) Aged >= 18 years old and onset age <= 45 years old, both male and female; (4) Sign informed consent and ensure the compliance of the experiment; (5) Women of childbearing age were confirmed to have no pregnancy by testing, and there was no pregnancy plan during the whole trial period; (6) There was no history of tuberculosis infection and active tuberculosis.
Exclusion criteria
Exclusion criteria: (1) Combined with other types of autoimmune diseases; (2) Cancer and cancer patients; (3) Patients with allergic constitution or allergic to the test drug or patients with serious adverse reactions after using the test drug; (4) Lactation or pregnancy women; (5) Patients with mania, depression and other mental disorders; (6) People with a history of infectious diseases such as tuberculosis, hepatitis B and HIV carriers and other infectious diseases; (7) Medical diseases with poor control, such as diabetes, hypertension and hyperlipidemia, etc; (8) Those who had a history of opioid analgesics, sedative hypnotics and alcohol abuse; (9) Combined with severe liver and kidney disease or severe damage of liver and kidney function; (10) Patients with blood system diseases; (11) Poor compliance, unable to meet the follow-up requirements.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the ASAS40 response rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| the ASAS5/6 response rate in patients;the ASAS partial remission response rate;the ASAS20 response rate; | — |
Countries
China
Contacts
Public ContactRenfu Quan
The Affiliated JiangNan Hospital of Zhejiang Chinese Medical University
Outcome results
None listed