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Clinical efficacy evaluation of Jingxin Zhidong formula in the treatment of moderate and severe Tic Disorder

Clinical efficacy evaluation of Jingxin Zhidong formula in the treatment of moderate and severe Tic Disorder and the logistic analysis of influencing factors

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2100004402
Enrollment
Unknown
Registered
2020-11-02
Start date
2014-01-01
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tic Disorder

Interventions

Sponsors

Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Children with TD who visited the Department of Pediatrics of Guang'anmen Hospital from January 2014 to December 2015; 2. Aged 8-11 years; 3. All meet the requirements of 2000 DSM - ? - TR diagnostic criteria and TCM syndrome differentiation criteria for children with tic disorder (head and body twitch, blinking and pouting, throat cleaning, or frowning and nose shrugging, or corner twitch, or sputum in throat, or abnormal voice, etc.) were discussed When heavy, and see temper irritable, or timid, easy to nervous, or suspicious, or easy to be wronged, or easy to excited, or sleep slowly, or sleep not solid, take food can, stool regulation, tongue light red or red, thin white or white fur, pulse string or slippery string.) 4. The course of disease is more than one year, the Yale Global Tic Severity Scale modified (YGTSS) score is between 40 and 70 (there is no clear diagnostic criteria for refractory tic disorder, the Yale Global Tic Severity Scale modified (YGTSS) score between 40 and 70 is refractory tic disorder), no use of Chinese and Western medicine or 6 months before treatment There was no use of Chinese and Western medicine in three months. 5. All the children were signed by their parents and obtained the informed consent from the medical ethics committee of Guang'anmen Hospital.

Exclusion criteria

Exclusion criteria: 1. Patients with hepatolenticular degeneration, rheumatic chorea, migraine in children, epilepsy and mental retardation; 2. Patients with history of schizophrenia, etc; 3. Patients with history of genetic metabolism; 4. Patients with severe physical diseases; 5. Patients with arrhythmia and abnormal liver and kidney function; 6. Patients with history of drug allergy; 7. Children and their parents do not agree to participate in the treatment.

Design outcomes

Primary

MeasureTime frame
YGTSS score;

Secondary

MeasureTime frame
TCM syndrome rating scale score;Adverse reaction scale score;

Countries

China

Contacts

Public ContactFei Han

Guang'anmen Hospital of China Academy of Chinese Medical Sciences

hanfei@gamyy.cn+86 13693134383

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026