The effects of Chinese herbal prescription (Liang-Xue-Xiao-Feng Powder) on the residence/survival of tissue-resident memory CD8+T cells in psoriasis epidermis

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ITMCTR

Registry ID

ITMCTR2100004386

Enrollment

Unknown

Registered

2021-02-04

Start date

2021-03-20

Completion date

Unknown

Last updated

2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Psoriasis

Interventions

Healthy volunteer group:None

treatment group :Chinese herbal prescription(Liang-Xue-Xiao-Feng Powder)

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnosis of PV; 2. A diagnosis of the blood-heat syndrome; 3. Aged 18 to 70 years; 4. Voluntarily participate in this study; Ability to sign informed consent; Agree to accept the treatment.

Exclusion criteria

Exclusion criteria: 1. With other skin diseases; 2. With other Severe systemic chronic wasting disease; 3. With mental disease; 4. Psoriasis of joint type, pustular type and erythrodermic type; 5. Received systemic glucocorticoids, retinoids or methotrexate medication within a month, or who received topical glucocorticoids within 2 weeks; 6. Scar diathesis; 7. Pregnant women.

Design outcomes

Primary

Measure	Time frame
IL-22;IFN-?;CD103;Psoriasis area and severity index;IL-17A;TNF-a;CD69;	—

Secondary

Measure	Time frame
epidermal thickness;Isolation and amplification of CD8 + TRM cells;Itching score;	—

Countries

China

Contacts

Public ContactPingsheng Hao

Hospital of Chengdu University of Traditional Chinese Medicine

hpswl@126.com+86 13881965024

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026