Novel Coronavirus Pneumonia (COVID-19)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Conform to the diagnostic criteria of COVID-19(Guidelines for the diagnosis and treatment of coronavirus disease 2020(trial version eighth))Patients who met the discharge standard and had negative neocoronavirus nucleic acid detection after discharge 2) Aged 18-75 years; 3) Having clinical manifestations of respiratory symptoms or fatigue; 4) Patient informed consent.
Exclusion criteria
Exclusion criteria: 1) Patients who have undergone operations that affect lung function, such as lung transplantation, lung resection, lung volume reduction, etc; 2) Dependent on mechanical ventilation to maintain lung function, such as ventilator; 3) Combined with chronic lung diseases that affect lung function, such as severe chronic obstructive pulmonary disease; 4) Patients with heart function related diseases, such as heart failure and pacemaker installation; 5) Severe underlying diseases affecting survival, including uncontrolled heart, kidney, digestive, blood diseases, neuropsychiatric diseases, immune diseases, metabolic diseases, malignant tumors, severe malnutrition, etc; 6) Resting heart rate > 120 / min; 7) Systolic blood pressure > 180mmhg, diastolic blood pressure > 100mmhg; 8) Unstable angina pectoris or myocardial infarction in recent 1 month; 9) Severe obesity (BMI > 30 kg / m2); 10) Allergic constitution, allergic to the drug components involved in the treatment program; 11) Pregnant or lactating women; 12) Disabled people who can't complete the collection of efficacy evaluation indicators; 13) Mental state can not cooperate, suffering from mental illness, no self-control, can not express clearly; 14) Participants in other clinical trials; 15) According to the judgment of the researchers, there will be patients with complications or poor compliance that affect the efficacy and safety evaluation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| modified Medical Research Council Dyspnea Scale (MMRC);Borg perceived fatigue scale;Visual analogue scale for cough; | — |
Secondary
| Measure | Time frame |
|---|---|
| 6 minutes walking distance;Blood oxygen saturation;Immune inflammation index;Depression Scale (PHQ-9), anxiety scale (GAD-7);Chest CT;TCM syndrome score; | — |
Countries
China
Contacts
Shijiazhuang People's Hospital