osteoarthritis
Conditions
Sponsors
Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1. Knee joint pain (pain for more than ten days occurred at least twice in the past year); 2. Imaging standards (K-L grade 0 grade I or grade II, of which K-L grade II only includes osteophyte formation); 3. MRI indicators: MRI found any 2 of the following 4 items: (1) Cartilage morphology WORMS score of 3-6 points; (2) Cartilage BLOKS score 2, 3; (3) Meniscus BLOKS score 3, 4; (4) Bone marrow edema WORMS score 2, 3 points.
Exclusion criteria
Exclusion criteria: 1. Patients with severe primary diseases such as cardiovascular, liver, kidney and hematopoietic system; 2. There are arthritic diseases such as rheumatoid arthritis and gouty arthritis, and other diseases that affect lower limb function; 3. People with allergies or allergies to multiple drugs; 4. Oral, intramuscular, joint injection or soft tissue injection of glucocorticoid within one month; 5. Long-term use of other drugs that affect the efficacy and safety determination and comprehensive treatment; 6. Those who are not suitable for MRI examination.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| T2 values; | — |
Countries
China
Contacts
Public Contactyangguangyue
Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed