Major depressive disorder
Conditions
Interventions
Sponsors
Shandong Mental Health Center
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients in the community; 2. Patients who met the ICD-10 diagnostic criteria for depressive disorder (F32 depressive episode or f33 recurrent depressive disorder); 3. Patients aged 18-65, male or female; 4. Subjects with 17 or more HAMD scores at baseline; 5. Informed consent signed by the patient or his legal guardian;
Exclusion criteria
Exclusion criteria: 1. Patients with serious suicidal tendency; 2. Patients with psychotic symptoms such as hallucination and delusion; 3. Patients with serious or unstable heart, liver, kidney, endocrine, blood and other internal diseases; 4. Patients with history of epilepsy; 5. Patients with diagnosis of alcohol and drug dependence within one year; 6. Patients with depression secondary to other mental or physical diseases; 7. Women who are lactating, pregnant or likely to be pregnant during the trial; 8. Patients currently using antidepressants; 9. Patients who failed to use SSRIs antidepressants in the past; 10. Patients without supervision or unable to take medicine according to doctor's advice; 11. Patients with bipolar disorder.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Morisky Medication Adherence Scale;TDM;Clinical Global Impression;Hamilton Depression Scale;Hamilton Anxiety Scale;Montgomery Asberg depression rating scale;Treatment Emergent Symptom Scale; | — |
Countries
China
Contacts
Public ContactGuanglei Xun
Shandong Mental Health Center
Outcome results
None listed