Amblyopia in children and adolescents
Conditions
Interventions
Sponsors
Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
6 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1. Age: 6-12 years old; 2. Anisometropic amblyopia should meet at least one of the following criteria: a. After cycloplegia, the difference between the equivalent spherical degrees of the eyes in refraction is >= 1.50 D. b. After ciliary muscle paralysis, the difference between the optometry and the cylinder lens is >= 1.00 D. 3. Vision: a. The best corrected visual acuity for amblyopic eyes is between 0.1 and 0.8. b. The visual acuity difference between the two eyes is more than 2 lines. 4. There are no other organic diseases affecting vision in both eyes, and form deprivation factors (leukoplakia, congenital cataract, complete ptosis, etc.) are excluded. 5. Informed consent, and voluntarily sign the informed consent, in line with ethical standards; the process of obtaining the informed consent should comply with GCP regulations. Only those who meet the above conditions can be selected.
Exclusion criteria
Exclusion criteria: 1. After ciliary muscle paralysis, the equivalent spherical degree of refraction is <= -6.0D. 2. Patients with organic eye diseases that can cause form deprivation, such as corneal leukoplakia, congenital cataracts, and complete ptosis. 3. According to the judgment of the investigator, other lesions that reduce the possibility of enrollment or complicate enrollment are likely to cause loss to follow-up. 4. Patients with mental or legal disabilities. 5. Those who are participating in other clinical trials. If one of the above matches, it will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| best corrected visual acuity;oxyhemoglobin;deoxyhemoglobin;Total hemoglobin;Diopter after pupil dilation; | — |
Secondary
| Measure | Time frame |
|---|---|
| VEP;stereopsis;contrast sensitivity;PRA;NRA; | — |
Countries
China
Contacts
Public ContactHongsheng Bi
Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine
Outcome results
None listed