intracerebral hemorrhage
Conditions
Interventions
Sponsors
Hospital (T.C.M) Affiliated to Southwest Medical University
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) The cases are in accordance with the diagnostic criteria of hemorrhagic apoplexy in traditional Chinese medicine and cerebral hemorrhage in western medicine; (2) Aged 40 to 75 years old and the course of disease within 24 hours from the onset of the disease; (3) No serious dysfunction of heart, liver, kidney and blood system; (4) The site of hemorrhage: supratentorial and basal ganglia, and the hematoma did not break into the ventricle; (5) The volume of hematoma is below 30ml; (6) The (mRS) score of the modified Rankin scale was between 0 and 1 before onset, and the mRS score >=2 before entering the group; (7) Those who sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Secondary cerebral hemorrhage of various causes (including intracranial aneurysm rupture, arteriovenous malformation or tumor hemorrhage, drug-related cerebral hemorrhage, etc.); subarachnoid hemorrhage; mixed stroke; multifocal hemorrhage; basal ganglia hemorrhage breaking into the ventricle; cerebral hernia formation; midline structure shift more than 5mm; ipsilateral ventricular compression occlusion more than 1x2. The ipsilateral cistern and sulcus were blurred or disappeared, and the volume of hematoma was > 30ml; (2) Those with a history of cerebral hemorrhage in the past six months; (3) Patients with gastrointestinal bleeding; (4) There are serious complications, such as heart, liver and kidney insufficiency, hematopathy, malignant tumor and severe infection, mental patients and so on; (5) Pregnant or lactating women; (6) Those who are allergic to any of the drug ingredients in this scheme; (7) Those who need surgical treatment; (8) There are metal implants in the body, claustrophobia and other patients who can not complete MRI.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| modified Rankin scale, mRS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Glasgow Coma Scale, GCS;parameter of blood-brain barrier permeability, Ktrans;Barthel Index, BI;National Institute of Health stroke scale, NIHSS;Recurrence rate of cerebrovascular events;variation of intracranial hematoma; | — |
Countries
China
Contacts
Public ContactBai Xue
Hospital (T.C.M) Affiliated to Southwest Medical University
Outcome results
None listed