Postoperative nausea and vomiting
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Women aged 18-65 years; 2. Subjects with ASA grade I or II; 3. Patients scheduled for gynecological laparoscopic ovarian or uterine surgery under general anesthesia; 4. Patients who are expected to use opioids after operation; 5. Subjects whose estimated operation time (from anesthesia induction to wound closure) >= 1H; 6. Subjects who voluntarily participated in the trial and signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Pregnant, lactating or menstrual women and smoking women; 2. Patients scheduled for laparoscopic surgery for gynecological malignancies; 3. Patients with nausea, vomiting or both within 24 hours before operation; 4. Patients who received antiemetic drugs, opioids or glucocorticoids within 24 hours before operation; 5. Patients with severe hepatic and renal insufficiency, central nervous system injury, vertebrobasilar insufficiency, vestibular diseases, coagulation disorders or other blood diseases; 6. Patients with skin damage at acupuncture point or eczema and other skin diseases; 7. Subjects who participated in other studies in recent 3 months; 8. Patients known to be allergic to ondansetron or metoclopramide.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the incidence of PONV in the first 24 hours postoperative; | — |
Secondary
| Measure | Time frame |
|---|---|
| the incidence of PON, the incidence of POV and the incidence of PONV in other evaluation periods;rescue antiemetic need;assessment of satisfaction score;episodes of vomiting;pain intensity;credibility and expectancy;degree of nausea;Time to first flatus;assessment of total postoperative analgesics dosage; | — |
Countries
China
Contacts
College of Acupuncture and Massage, Beijing University of Traditional Chinese Medicine