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Evaluation of therapeutic effect of Bushen Zhiwang decoction on bone destruction in patients with Rheumatoid Arthritis and cohort study of bone destruction markers

Evaluation of Ttherapeutic effect of Bushen Zhiwang decoction on bone destruction in patients with Rheumatoid Arthritis and cohort study of bone destruction markers

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ITMCTR
Registry ID
ITMCTR2100004230
Enrollment
Unknown
Registered
2020-10-10
Start date
2020-10-01
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rheumatoid Arthritis

Interventions

Sponsors

Beijing University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 16-70 years; 2. Patients who meet the diagnostic criteria of RA and the diagnostic criteria of traditional Chinese medicine for liver and kidney deficiency syndrome; 3. Patients with anteroposterior radiographs of both hands (including wrist) before and after treatment for one year; 4. Patients with wrist X-ray grade I-III; 5. Patients with informed consent.

Exclusion criteria

Exclusion criteria: 1. Mental patients; 2. Patients with severe malnutrition or severe damage of heart, brain, kidney and hematopoietic system; 3. Patients with other rheumatic diseases; 4. Patients with joint dysfunction; 5. Patients with incomplete information.

Design outcomes

Primary

MeasureTime frame
Sharp Scoring;

Secondary

MeasureTime frame
Rankl;

Countries

China

Contacts

Public ContactXu Yuan

China-Japan Friendship Hospital

xuyuan2004020@163.com+86 13691548422

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026