Diabetic Nephropathy
Conditions
Interventions
Control Group:(1)Diabetes health education, low-sodium and low-fat diet, high-quality low-protein diet, protein intake of 0.8 g/kg-1·d-1, dietary sodium intake <2g/d
psychological counseling for patients to actively cooperate with the current treatment.(2) Basic drug therapy: If blood glucose control is unsatisfactory, according to the recommendations of the "Chin
Experimental Group:(1)Diabetes health education, low-sodium and low-fat diet, high-quality low-protein diet, protein intake of 0.8 g/kg-1·d-1, dietary sodium intake <2g/d
Sponsors
Integrated Chinese and Western Medicine Hospital, Cangzhou, Province of Hebei
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1)Meets diagnostic criteria for Type 2 diabetes mellitus; (2) Meets diagnostic criteria for Diabetic kidney disease (DKD) Stage A2; (3) Chinese medical pattern identification: Qi and Yin deficiency (with blood stasis) syndrome; (4) HbA1c = 8.5%; (5) eGFR = 60mL/min/1.73 m²; (6) Age 18–75 years, gender; (7) Signed informed consent form.
Exclusion criteria
Exclusion criteria: (1) Patients with severe cardiovascular, cerebrovascular, hepatic, or hematopoietic system diseases; (2) Patients on triple antihypertensive therapy with systolic blood pressure =160 mmHg; (3) Pregnant or breastfeeding women; (4) Patients with nephropathy caused by other reasons; (5) Patients allergic to the study drug; (6) Patients who have participated in or are currently participating in other drug clinical trials within the past three months, or are receiving hormonal or immunosuppressive therapy; (7) Patients who have used SGLT2i drugs within the past three months prior to enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Urine Microalbumin/Urine Creatinine; | — |
Secondary
| Measure | Time frame |
|---|---|
| Glomerular filtration rate,eGFR;TCM Syndrome Score; | — |
Countries
China
Contacts
Public ContactLü Shuquan
Integrated Chinese and Western Medicine Hospital, Cangzhou, Province of Hebei
Outcome results
None listed