Atopic Dermatitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1: In line with the diagnosis of AD Chinese and Western medicine 2: Eczema area and severity index ( EASI ) score = 15. 3: Patients with the researcher 's overall score ( IGA ) = 3 4: AD patients who had received at least 12 weeks of duplizumab or JAK inhibitor treatment in the past year, but the improvement of skin lesions did not reach EASI 50 or pruritus NRS score = 4 or DLQI score = 6
Exclusion criteria
Exclusion criteria: 1: Patients with acute or chronic skin infections, psoriasis, scabies, or allergic or contact dermatitis 2: Patients with chronic systemic diseases or tumors such as circulatory, respiratory, digestive and hematopoietic systems 3: psychotic 4: Pregnant women and lactating patients 5: Combined drug abuse, alcohol abusers
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Eczema Area and Severity Index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Immunoglobulin E, IgE;eosinophil,OES;Interleukin 4, IL-4;Interleukin 13, IL-13;Interleukin 17, IL-17;Investigator Global Assessment;Scoring Atopic Dermatitis, SCORAD;Visual Analogue Scale, VAS;Patient Oriented Eczema Measure, POEM;Atopic Dermatitis Control Tool, ADCT;Dermatology Life Quality Index/Children's Dermatology Life Quality Index, DLQI/CDLQI; | — |
Countries
China
Contacts
Guangdong Provincial Hospital of Chinese Medicine