Chronic Migraine
Conditions
Interventions
Acupuncture group:soothing liver and regulating the spirit acupuncture
Healthy Control Group:None
Sponsors
Affiliated Hospital of Shandong University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Inclusion criteria for chronic migraine patients: (1) Meet the diagnostic criteria for chronic migraine; (2) Age 18-65 years, right-handed; (3) Have not undergone acupuncture treatment in the past 3 months; (4) Voluntarily participate and sign the informed consent form; (5) Have had migraines for at least 1 year prior to screening, with onset of migraines before the age of 50. 2. Inclusion criteria for healthy subjects: (1) Healthy physical examination, without organic or significant functional diseases; (2) Age 18-65 years, right-handed; (3) Have not undergone acupuncture treatment in the past 3 months; (4) Voluntarily participate and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Those prone to concurrent infections and bleeding, lactating women, pregnant women, and individuals with allergic constitutions (especially those allergic to metal acupuncture needles); 2. Individuals with severe systemic diseases such as cardiovascular, hepatic, renal, or cerebral conditions; 3. Patients with mental disorders or somatization disorders who are unable to independently complete this clinical study; 4. Those who have taken psychotropic or vasoactive medications within the past three months; 5. Individuals with headaches caused by excessive use of analgesic medications; 6. Those with contraindications for MRI scans, such as implanted metallic devices or claustrophobia; 7. Individuals unable to cooperate with the treatment or currently participating in other related clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cranial MRI data;Monthly headache days; | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual Analogue Scale;Headache symptom score;migraine-specific quality of life questionnaire; | — |
Countries
China
Contacts
Public ContactJing Han
Affiliated hospital of Shandong University of Traditional Chinese Medicine
Outcome results
None listed