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A Clinical Translational Study on Synergistic Acupuncture-BCI Intervention Based on Multimodal Navigation of the Frontoparietal Network in Post-Stroke Cognitive Impairment.

A Clinical Translational Study on Synergistic Acupuncture-BCI Intervention Based on Multimodal Navigation of the Frontoparietal Network in Post-Stroke Cognitive Impairment.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2026001637
Enrollment
Unknown
Registered
2026-06-30
Start date
2026-07-06
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-stroke cognitive impairment

Interventions

Acupuncture Combined with BCI Treatment Group:Acupuncture, brain-computer interface
BCI Treatment Group:Brain-Computer Interface
Sham Electroacupuncture Combined with BCI Treatment Group:Dummy needle, brain-computer interface

Sponsors

Guangdong Provincial Traditional Chinese Medicine University Town Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Meets the diagnostic criteria for stroke established by the Fourth National Cerebrovascular Disease Academic Conference; (2) Within 3-6 months after the first ischemic stroke; (3) MoCA score <26 (if education duration =12 years, MoCA <24), and able to cooperate with the assessment; (4) Confirmed cerebrovascular lesion by CT/MRI; (5) Age between 40-80 years; (6) Assessed as right-handed by the Edinburgh Handedness Inventory; (7) Bruunstrom stage 1-4; (8) First-time acupuncture treatment or no acupuncture treatment in the past three months, and no use of drugs that may affect neuroplasticity in the past three months; (9) Possesses basic tolerance to acupuncture; (10) Voluntarily signs the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Unable to cooperate to complete the experiment, with severe cognitive dysfunction or aphasia; (2) Unstable condition or changes in condition during the experiment that affect the results; (3) Severe heart, lung, liver, or kidney diseases that prevent completion of the experiment; (4) Severe mental disorders; (5) Vision or visual field impairment that affects the conduct of the experiment; (6) Unable to cooperate with the experiment for various reasons; (7) History of epilepsy.

Design outcomes

Primary

MeasureTime frame
Brain-Computer Interface Response Rate;Results of the spatial working memory span paradigm.;

Secondary

MeasureTime frame
Montreal Cognitive Assessment;Trail Making Test;Digit Span Test;Verbal Fluency Test;Near-infrared brain functional imaging assessment of brain region activation levels;Near-infrared brain functional imaging assessment of functional connectivity in brain regions.;

Countries

China

Contacts

Public ContactOu Haining

Guangdong Provincial Hospital of Traditional Chinese Medicine

Haining@gzucm.edu.cn+86 186 8890 6213

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Aug 10, 2026