Sepsis - induced gastrointestinal dysfunction.
Conditions
Interventions
The control group :Based on the Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021 and the 2012 European Society of Intensive Care Medicine (ESICM) Cons
2) Stabilization of the internal environment and improvement of tissue perfusion and oxygenation
3) Early initiation of enteral nutrition
4) Symptomatic management (gastrointestinal decompression, antiemetic therapy, etc.)
5) Maintenance of the intestinal microecological environment, etc.
The electroacupuncture group:Based on the control group treatment, the electroacupuncture group additionally received electroacupuncture at the following acupoints: Zhongwan (CV12), Tianshu (ST25), Ne
Sponsors
Jiangsu Hospital of Chinese Medicine.
Eligibility
Sex/Gender
All
Age
15 Years to 100 Years
Inclusion criteria
Inclusion criteria: Compliance with the diagnostic criteria of Sepsis 3.0. AGI grade of =1. Patients aged =18 years of any sex. Patients who have been informed and have signed the consent form.
Exclusion criteria
Exclusion criteria: Patients intolerant to acupuncture. Pregnant or breastfeeding women. Patients with a history of severe gastrointestinal diseases: such as severe peptic ulcer bleeding gastrointestinal surgery or trauma within the past 2 years or incomplete gastrointestinal anatomy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| enteral nutrition tolerance score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Acute Gastrointestinal Ultrasound Score (AGIUS) ;Brain-gut peptides: gastrin (GAS), motilin (MTL), cholecystokinin (CCK), and somatostatin (SS).;Feeding volume [kcal/(kg·d)];AGI grading ;NUTRIC score;Duration of mechanical ventilation ;28-day mortality;Length of ICU stay ;Nutritional index; | — |
Countries
China
Contacts
Public ContactGengYanxia
Jiangsu Hospital of Chinese Medicine.
Outcome results
None listed