Adult respiratory infectious diseases
Conditions
Interventions
Sponsors
Guangdong Provincial Hospital of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria for Retrospective Cohort Study Satisfy the diagnostic criteria for influenza defined by the Diagnosis and Treatment Protocol for Influenza (2025): patients with clinical manifestations of influenza including fever, headache and other related symptoms, plus one or more positive etiological test findings as listed below: (1) Positive influenza antigen test; (2) Positive influenza viral nucleic acid assay; (3) Positive influenza virus culture and isolation; (4) Seroconversion of influenza virus IgG antibodies, or a =4-fold rise in IgG antibody titers in the convalescent phase relative to the acute phase. Age = 18 years. No gender limitations. Received treatment with traditional Chinese medicine (TCM) or integrated Chinese and Western medicine. Inclusion Criteria for Prospective Cohort Study Satisfy the diagnostic criteria for influenza defined by the Diagnosis and Treatment Protocol for Influenza (2025): patients with clinical manifestations of influenza including fever, headache and other related symptoms, plus one or more positive etiological test findings as listed below: (1) Positive influenza antigen test; (2) Positive influenza viral nucleic acid assay; (3) Positive influenza virus culture and isolation; (4) Seroconversion of influenza virus IgG antibodies, or a =4-fold rise in IgG antibody titers in the convalescent phase relative to the acute phase. Age = 18 years, with no gender limitations. Capable of completing full data collection and follow-up procedures as required. Voluntarily enroll in the study and provide written informed consent.
Exclusion criteria
Exclusion criteria: Exclusion Criteria for Retrospective Cohort 1. Cases with a missing rate of clinical data exceeding 30%, including traditional Chinese medicine (TCM) syndrome types and western medicine laboratory and examination indicators. 2. Cases with incomplete records of key diagnosis and treatment information such as records of TCM and western medicine medication and clinical outcome indicators. Exclusion Criteria for Prospective Cohort 1. Patients complicated with severe vital organ failure of the heart, liver, kidney and other organs, or underlying diseases such as malignant tumors and immunodeficiency, whose disease progression or treatment may mask the natural course of respiratory infectious diseases as well as the effects of TCM and integrated traditional Chinese and western medicine diagnosis and treatment. 2. Patients who have not received TCM treatment or integrated traditional Chinese and western medicine treatment. 3. Patients with severe cognitive impairment, mental illness or communication disorders who are unable to cooperate with data collection. 4. Those who have participated in other clinical trials recently that may affect the results of this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 6-point clinical status; | — |
Secondary
| Measure | Time frame |
|---|---|
| Symptom improvement (including fever, cough, etc.);Length of hospital stay;Severe case conversion rate;Case fatality rate; | — |
Countries
China
Contacts
Public ContactRongyuan Yang
Guangdong Provincial Hospital of Chinese Medicine
Outcome results
None listed