Rheumatoid Arthritis
Conditions
Interventions
experimental group:Auricular concha electroacupuncture + methotrexate + celecoxib
control group:methotrexate + celecoxib
Sponsors
General Hospital of Eastern Theater Command, PLA
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) Aged 18–75 years; 2) Meet the classification criteria established by the 2010 ACR/EULAR; 3) Meet the criteria for active disease based on DAS28 score (DAS28 = 2.6); 4) No treatment with biological agents or JAK inhibitors within 4 weeks prior to enrollment, or currently receiving methotrexate/celecoxib with stable dosage for at least 4 weeks; 5) Understand the study content and purpose, voluntarily sign the informed consent form, and be willing to actively cooperate with acupuncture treatment.
Exclusion criteria
Exclusion criteria: 1) Those who do not meet the above inclusion criteria; 2) Overlap with other autoimmune diseases, such as systemic lupus erythematosus, Sjögren's syndrome, autoimmune liver disease, etc.; 3) Complicated with severe diseases involving the cardiovascular, pulmonary, liver, kidney, hematopoietic systems, or malignant tumors; 4) History of previous vagus nerve surgery; 5) Presence of implantable or portable electromechanical medical devices, such as pacemakers, defibrillators, cochlear implants, etc.; 6) Clinical history of syncope or epilepsy/seizures.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ACR response criteria; | — |
Secondary
| Measure | Time frame |
|---|---|
| Chinese Medicine Efficacy Evaluation Criteria;erythrocyte sedimentation rate (ESR);RF(rheumatoid factors);C-reactive protein; | — |
Countries
china
Contacts
Public Contacthumengdi
General Hospital of Eastern Theater Command, PLA
Outcome results
None listed