chronic obstructive pulmonary disease
Conditions
Interventions
experimental group:Health education + dual/triple drug inhalation therapy + traditional Chinese medicine granules
control group:Health education + dual/triple drug inhalation therapy + placebo of traditional Chinese medicine
Sponsors
Affiliated Hospital of Liaoning University of Traditional Chinese Medicine
Eligibility
Sex/Gender
Male
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Patients diagnosed with stable chronic obstructive pulmonary disease (COPD); (2) Patients with stable COPD who have frequent acute exacerbations; (3) Meeting the diagnostic criteria for lung qi deficiency syndrome or lung-spleen qi deficiency syndrome in traditional Chinese medicine; (4) Age range: 40 years = age < 80 years, gender unrestricted; (5) Undergoing a 2-week washout period before enrollment; (6) Voluntary participants with good compliance and having signed the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Patients with other respiratory system diseases such as respiratory tract infection, bronchiectasis, bronchial asthma, interstitial lung disease, and eosinophilic lung disease, etc. (2) Patients allergic to the ingredients of the formula. (3) Patients with concurrent malignant tumors, heart failure, arrhythmia, neurological diseases, hematological diseases, mental illness, or severe liver and kidney dysfunction. (4) Pregnant or lactating women. (5) Patients who are unable to complete pulmonary function tests, blood tests, and questionnaires for scoring. (6) Patients who have participated in other drug clinical trials within the past three months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The number of acute exacerbations within one year; | — |
Secondary
| Measure | Time frame |
|---|---|
| quality of life;lung function;BODE index;6-minute walk test distance;Clinical symptoms and signs;Shortness of Breath Questionnaire; | — |
Countries
China
Contacts
Public ContactLijian Pang
Affiliated Hospital of Liaoning University of Traditional Chinese Medicine
Outcome results
None listed