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A Study on Chushi Shengfa Decoction for the Treatment of Male Androgenetic Alopecia Based on Machine Learning and Multi-Omics Analysis: A Randomized Controlled Trial (RCT)

Integration of Traditional Chinese and Western Medicine for Prevention and Treatment of Hair and Scar Disorders: Leadership Talent Training Program

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2026001600
Enrollment
Unknown
Registered
2026-06-26
Start date
2026-06-23
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Androgenetic alopecia

Interventions

Control Group:Orally administered finasteride, topically applied minoxidil.
Experimental Group:Oral finasteride, topical minoxidil, and oral Dampness-Removing Hair Growth Decoction.

Sponsors

China-Japan Friendship Hospital
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Male patients aged 20 to 40 years old; 2. Confirmed as AGA through clinical presentation and hair microscopy; 3. Hamilton-Norwood classification: III vertex, grade IV; 4. TCM differential diagnosis: damp-heat syndrome; 5. No AGA-related treatments in the past 3 months; 6. Able to adhere to medication and follow-up, and willing to sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Individuals with allergies to the study drug or its components, or those unable to tolerate related therapies; 2. Individuals with other hair diseases; 3. Individuals with severe liver or kidney dysfunction; 4. Individuals who have participated in other clinical trials within the past 3 months; 5. Individuals who have used any systemic antibiotics, probiotic formulations, prebiotic supplements, immunosuppressants, or other lipid-lowering drugs affecting bile acid metabolism within the past 3 months.

Design outcomes

Primary

MeasureTime frame
Efficient (clinical indicators and hair microscopy indicators);

Secondary

MeasureTime frame
Improvement in Damp-Heat Syndrome Scores in Traditional Chinese Medicine;Hair Growth Condition Assessment (seven-point rating system and BASP classification);Scalp Health Condition Improvement;The improvement of other dermoscopic signs;

Countries

China

Contacts

Public ContactYang Dingquan

China-Japan Friendship Hospital

ydqlx@163.com010-84205122

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Aug 10, 2026